Remember Instagram's 24-hour window: when the last interaction was more than 24 hours ago, automations pause until the user restarts the conversation.
Make sure the user's window is open and provide us with some additional information and screenshots.

Hi, this is not about the 24-hour window. The automation doesn’t work from the start. Users click on the buttons and the automation does not start.

The same thing happens to me. Automation is not activated when the keyword is commented on. Losing money.